![]() The world health organization has announced the novel corona virus disease as COVID-19 and declared it as pandemic globally on 11 February 2020. ![]() Various drug molecules can be designed by applying computational tools to explore the drug candidates for treatment of Coronavirus infection. ![]() Due to increase in the availability of information regarding various biological targets of different disease states, computational approaches such as molecular docking, de novo design, molecular similarity calculation, virtual screening, pharmacophore-based modeling and pharmacophore mapping have been applied extensively. This approach is mainly applied in various phases of drug discovery process including target identification, target validation, lead identification and lead optimization. Among these methods, the computational approach is considered as an efficient strategy to accelerate and economize the drug discovery process. There are different techniques involved in the drug development process which include random screening, computational approach, molecular manipulation and serendipitous research. Background: Drug discovery and development process is an expensive, complex, time-consuming and risky.
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